Clerodane diterpenes: sources, structures, and biological activities

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New rearranged clerodane diterpenes from Tinospora baenzigeri.

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Biological activities and cytotoxicity of diterpenes from Copaifera spp. Oleoresins.

Copaifera spp. are Amazonian species widely studied and whose oleoresins are used by local people for various medicinal purposes. However, a detailed study of the activity of the main phytochemical components of these oleoresins remains to be done. Here, we studied the cytotoxicity and in vitro anti-inflammatory effects of six diterpene acids: copalic, 3-hydroxy-copalic, 3-acetoxy-copalic, hard...

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Three new clerodane diterpenes from Polyalthia longifolia var. pendula.

Three new clerodane diterpenes, (4→2)-abeo-cleroda-2,13E-dien-2,14-dioic acid (1), (4→2)-abeo-2,13-diformyl-cleroda-2,13E-dien-14-oic acid (2), and 16(R&S)- methoxycleroda-4(18),13-dien-15,16-olide (3), were isolated from the unripe fruit of Polyalthia longifolia var. pendula (Annonaceae) together with five known compounds (4-8). The structures of all isolates were determined by spectroscop...

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Neo-clerodane diterpenes from the hallucinogenic sage Salvia divinorum.

Seven new neo-clerodane diterpenes, salvidivins A (2), B, (3), C (4), and D (5), salvinorins H (6) and I (7), and divinatorin [corrected] F (8), along with eight known neo-clerodane diterpenes, salvinorins A (1)-F, divinatorins A and B, and seven other constituents, were isolated from the hallucinogenic sage Salvia divinorum. The structures of 1-7 were elucidated on the basis of 2D NMR spectros...

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ژورنال

عنوان ژورنال: Natural Product Reports

سال: 2016

ISSN: 0265-0568,1460-4752

DOI: 10.1039/c5np00137d